As the talk show host's 25-year-long show ends, THR highlights the most memorable moments.
Tom Cruise shocked Oprah and the world when he now-infamously declared his love for soon-to-be wife Katie Holmes in 2005 by declaring "I'm in love" and jumping up and down on her couch.
Aided by guest John Travolta (a Qantas pilot) the Queen of Media shocked her studio audience last December by giving them a trip to Australia .
In December of 2009, Oprah shot a Christmas special at the White House with President Obama and the First Lady where she asked Michelle about her favorite gift.
In 1993, the King of Pop beatboxed and gave an impromptu performance for the talk show host during an exclusive interview.
Jennifer Hudson on 'The Oprah Winfrey Show'
Oscar winner and former American Idol contestant Jennifer Hudson talked weight loss, and broke her silence on the murder of her mother, brother and nephew, with Oprah in February 2011.
The studio confirmed the casting on Monday. Read More
Phillip Phillips says he's been "manipulated" and in a move with huge implications, he is seeking to void his recording, management and merchandising deals with 19 Entertainment. Read More
Hollywood's biggest stars are out to honor their own at the Shrine Auditorium in Los Angeles on January 25 View gallery
Hollywood's top onscreen talent were honored at Sunday's Screen Actors Guild Awards, held at the Shrine Auditorium in Los Angeles. View gallery
A slew of stars posed for exclusive portraits by Austin Hargrave at Rock & Reilly's Park City. View gallery
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