81 of Fall TV's Biggest Stars: THR's Exclusive Portraits

ABC's 'Marvel's Agents of SHIELD'

From left: Brett Dalton, Chloe Bennet, Clark Gregg, Ming-Na Wen, Elizabeth Henstridge and Iain De Castecker.

Premieres Sept. 24 at 8 p.m. on ABC.

NBC's 'The Michael J. Fox Show'

"Sometimes it's frustrating, and sometimes it's funny. I need to look at it that way, and I think other people will look at it that way," says Michael J. Fox on the reality of Parkinson's disease, the subject of his new comedy.

Premieres Sept. 26 at 9 p.m. on NBC.

CBS' 'The Crazy Ones'

"Lots and lots of stalking," is Sarah Michelle Gellar's answer to how she got cast in The Crazy Ones with Robin Williams.

Premieres Sept. 26 at 9 p.m. on CBS.

Fox's 'Brooklyn Nine-Nine'

"What I love most about my character is that he's smarter than I am," says Andy Samberg, sandwiched by Chelsea Peretti and Joe Lo Truglio.

Premieres Sept. 17 at 8:30 p.m. on Fox.

NBC's 'Ironside'

"He fights for truth, justice and the right to give a perp a good beatdown," says Blair Underwood of his Ironside character.

Premieres Oct. 2 at 10 p.m. on NBC.

NBC's 'The Blacklist'

James Spader stars as Red Reddington, the world's most wanted criminal who turns himself in and offers to give up everyone he has ever worked with. The catch: He will only work with a rookie FBI agent (Megan Boone).

Premieres Sept. 23 at 10 p.m. on NBC.

CBS' 'Mom'

Mom follows a single mother, played by Anna Faris, who attempts to start a new life in Napa Valley after battling alcoholism.

Premieres Sept. 23 at 9:30 p.m. on CBS.

CBS' 'Hostages'

"He walks a fine line between good and bad," says Dylan McDermott of his Hostages character, Duncan Carlisle. "It's a great way to go to work and not be arrested at the end of the day.

Premieres Sept. 23 at 10 p.m. on CBS.

NBC's 'Sean Saves the World'

Will & Grace alum Sean Hayes, who is a producer on Grimm and Hollywood Game Night, returns to NBC with a new comedy.

Premieres Oct. 3 at 9 p.m. on NBC.

CBS' 'Hostages'

Toni Collette plays Dr. Ellen Sanders, who — along with her family — is taken hostage by a rogue FBI agent.

Premieres Sept. 23 at 10 p.m. on CBS.

CBS' 'The Millers'

From left: J.B. Smoove and Will Arnett.

Premieres Oct. 3 at 8:30 p.m. on CBS.

ABC's 'Super Fun Night'

From left: Lauren Ash, Rebel Wilson, Kevin Bishop and Liza Lapira. "He offered to put out if I want with his production," Wilson says on teaming with executive producer Conan O'Brien.

Premieres Oct. 2 at 9:30 p.m. on ABC.

CBS' 'Mom'

Allison Janney stars in the Chuck Lorre co-created sitcom as Bonnie.

Premieres Sept. 23 at 9:30 p.m. on CBS.

Fox's 'Brooklyn Nine-Nine'

Andre Braugher is Capt. Ray Holt, commander of Brooklyn's 99th Precinct.

Premieres Sept. 17 at 8:30 p.m. on Fox.

Fox's 'Sleepy Hollow'

From left: Tom Mison and Nicole Beharie.

Premieres Sept. 16 at 9 p.m. on Fox.

Fox's 'Almost Human'

From left: Karl Urban and Michael Ealy.

Premieres Nov. 4 at 8 p.m. on Fox.

ABC's 'Trophy Wife'

From left: Natalie Morales, Malin Akerman and Michaela Watkins.

Premieres Sept. 24 at 9:30 p.m. on ABC.

Fox's 'Dads'

"He's deeply cynical but optimistic," says Seth Green (bottom left) of his Dads character. From top left: Peter Riegert, Martin Mull and Giovanni Ribisi.

Premieres Sept. 17 at 8 p.m. on Fox.

NBC's 'Sean Saves the World'

Smash veteran Megan Hilty joins the cast of Sean Hayes' new Thursday night comedy.

Premieres Oct. 3 at 9 p.m. on NBC.

CBS' 'The Crazy Ones'

James Wolk stars as Robin Williams' son, Zach, who works alongside his father at a Chicago ad agency.

Premieres Sept. 26 at 9 p.m. on CBS.

ABC's 'Once Upon a Time in Wonderland'

From left: Michael Socha, Peter Gadiot and Sophie Lowe.

Premieres Oct. 10 at 8 p.m. on ABC.

The CW's 'The Originals'

Joseph Morgan, as fan favorite Klaus, leads the New Orleans-set Vampire Diaries offshoot.

Premieres Oct. 3 at 9 p.m. on The CW.

ABC's 'Back in the Game'

James Caan stars in ABC's Back in the Game, a comedy about a former star softball player who moves back in with her father, a former athlete who is now a couch potato.

Premieres Sept. 25 at 8:30 p.m. on ABC.

Fox's 'Enlisted'

"I love that my character is torn between doing his best at his job and trying to be the best brother he can be," says Geoff Stults (far left), with Parker Young (center) and Chris Lowell.

Premieres Nov. 8 at 9:30 p.m. on Fox.

Fox's 'Almost Human'

"I love that my character is strong and in command in a very male context and yet is able to hold on to her feminine side," says Lili Taylor (left), seen here with Minka Kelly.

Premieres Nov. 4 at 8 p.m. on Fox.

ABC's 'Once Upon a Time in Wonderland'

Lost's Naveen Andrews plays Jafar in the Once Upon a Time spinoff.

Premieres Oct. 10 at 8 p.m. on ABC.

ABC's 'The Goldbergs'

Camera in hand, Goldbergs star Jeff Garlin poses for his close-up.

Premieres Sept. 24 at 9 p.m. on ABC.

NBC's 'The Michael J. Fox Show'

Breaking Bad's Betsy Brandt portrays Michael J. Fox's wife, Annie Henry, on The Michael J. Fox Show.

Premieres Sept. 26 at 9 p.m. on NBC.

CBS' 'The Millers'

Margo Martindale stars in the CBS comedy as Carol Miller, whose life is complicated when her son Tom (Will Arnett) informs her of his divorce.

Premieres Oct. 3 at 8:30 p.m. on CBS.

NBC's 'Welcome to the Family'

Mary McCormack stars as Mike O'Malley's wife in the comedy, which follows a white family and a Latino family who come together after their children fall in love.

Premieres Oct. 3 at 8:30 p.m. on NBC.

ABC's 'Back in the Game'

From left: Lenora Crichlow and Maggie Lawson.

Premieres Sept. 25 at 8:30 p.m. on ABC.

ABC's 'The Goldbergs'

Wendi McLendon-Covey stars in the single-camera 1980s-set comedy from Adam F. Goldberg.

Premieres Sept. 24 at 9 p.m. on ABC.

CBS' 'We Are Men'

From left: Tony Shalhoub, Jerry O'Connell, Chris Smith and Kal Penn.

Premieres Sept. 30 at 8:30 p.m. on CBS.

NBC's 'Ironside'

Spencer Grammer plays a member of Detective Robert Ironside's team on the upcoming NBC remake.

Premieres Oct. 2 at 10 p.m. on NBC.

The CW's 'The Originals'

Phoebe Tonkin works her way over from The Vampire Diaries to its spinoff this fall as werewolf Hayley.

Premieres Oct. 3 at 9 p.m. on The CW.

ABC's 'Lucky 7'

From left: Executive producer Jason Richman, Isiah Whitlock Jr., Lorraine Bruce, Anastasia Phillips, Luis Antonio Ramos and Matt Long.

Premieres Sept. 24 at 10 p.m. on ABC.

NBC's 'The Blacklist'

From left: Ryan Eggold and Megan Boone.

Premieres Sept. 23 at 10 p.m. on NBC.

NBC's 'Welcome to the Family'

Ella Rae Peck co-stars in the NBC comedy as Molly Yoder, who becomes pregnant, causing the Yoders to bond with the Hernandez family.

Premieres Oct. 3 at 8:30 p.m. on NBC.

ABC's 'Betrayal'

James Cromwell stars in creator David Zabel's hourlong drama about a photographer who begins an affair with a powerful lawyer.

Premieres Sept. 29 at 10 p.m. on ABC.

CBS' 'The Millers'

Beau Bridges plays Will Arnett's father, Tom Miller, in the upcoming CBS sitcom.

Premieres Oct. 3 at 8:30 p.m. on CBS.

Fox's 'Brooklyn Nine-Nine'

Terry Crews co-stars on the Fox comedy from Parks and Recreation's Mike Schur and Dan Goor as Sergeant Terry Jeffords.

Premieres Sept. 17 at 8:30 p.m. on Fox.

ABC's 'The Goldbergs'

Hayley Orrantia co-stars in the semi-autobiographical comedy from Adam F. Goldberg.

Premieres Sept. 24 at 9 p.m. on ABC.

ABC's 'The Goldbergs'

"He's slightly demented," says George Segal (right), with Sean Giambrone, of his Goldbergs character.

Premieres Sept. 24 at 9 p.m. on ABC.

NBC's 'Sean Saves the World'

Newcomer Samantha Isler co-stars in the upcoming Sean Hayes comedy as the Will & Grace vet's daughter, Ellie.

Premieres Oct. 3 at 9 p.m. on NBC.

CBS' 'Mom'

Mom co-stars comedian/Breaking Bad alum Matt Jones.

Premieres Sept. 23 at 9:30 p.m. on CBS.

CBS' 'The Crazy Ones'

Actress Amanda Setton will co-star in the CBS sitcom with Robin Williams and Sarah Michelle Gellar.

Premieres Sept. 26 at 9 p.m. on CBS.