In the new Hollywood Reporter, she makes digs at Vanity Fair’s Graydon Carter, the Kardashians and Ellen DeGeneres; “My brain is bleeding...I want to do something that’s more mindful and isn’t celebrity centered.”
2002: 'My Wife and Kids'
As a struggling actress, Handler played a number of bit parts, including a short stint on the ABC comedy starring Damon Wayans and Tisha Campbell-Martin.
2002: 'Girls Behaving Badly'
Handler beat out heavy competition to land a recurring role on Oxygen's Girls Behaving Badly, where five women prank unsuspecting victims.
2005: E! Commentator
The funny lady became a regular commentator on E!, hosting many of its "Best of" programs as well as the MSNBC opinion/analysis show "Scarborough Country."
2006: 'Chelsea Handler Show'
Handler debuted the Friday night sketch-comedy series on E!, spoofing celebrities, TV and the entertainment industry.
2007: 'Chelsea Lately'
E!'s late-night half-hour talk show, which draws 1 million viewers, mixed a cocktail of stand-up, pop-culture gossip reports and celebrity interviews.
2010: MTV Video Music Awards
The comic was panned for her hosting gig, but it drew more than 11 million viewers and became the network's third-most-watched telecast.
2011: 'After Lately'
A reality-inspired sitcom that claims to re-enact behind-the-scenes moments from the "Chelsea Lately" writing team has been picked up for a second season on E!
Handler landed a small cameo in Universal's 2011 hybrid-animated Easter bunny flick "Hop" and a role in Fox's upcoming action-comedy "This Means War."
2012: 'Are You There, Vodka? It's Me, Chelsea'
The NBC comedy, set to air as a midseason replacement, shares the same name as her best-seller and is loosely based on Handler's life.
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