"Not bad for a show canceled twice" is a popular line within the halls of Family Guy headquarters. At a celebration following another milestone for the series created, written and voiced by MacFarlane, a congratulatory banner from the studio and network read: "Two Cancellations, Zero FCC Fines, Zero Humanitarian Prizes. Congrats on 200 episodes."
The Family Guy spinoff, which was granted a third and fourth season, was co-created and voiced by Mike Henry, whose brother was a classmate of MacFarlane's at Rhode Island School of Design. "I'm fortunate to have befriended him," Henry says of MacFarlane, "and even more fortunate that he thought I was funny."
Now in its eighth season, American Dad! "has yet to become Family Guy," says MacFarlane of the reception -- and arguably the quality -- of his popular second Fox entry, adding: "If Family Guy is Cheers, American Dad! is Wings."
He co-wrote, produced and directed his first film, out in summer 2012, about an otherwise normal man who keeps a walking, talking teddy bear (voiced by MacFarlane). "It has an enormous amount of heart," he says. "Probably far more than people will be expecting from something to come out of my production and editing."
Of the series set for 2013, the left-leaning MacFarlane jokes, "I'm the first guy to express reservations about giving the extreme right wing something to point to that shows humans living alongside dinosaurs." (The art shown is a childhood sketch MacFarlane made of Fred Flintstone).
Unlike recent free agent Jay Leno, CBS has no heir apparent waiting in the wings for when Letterman steps down in 2015. Late-night neighbor Craig Ferguson is one choice, but no sure thing, so here is a rundown of 17 candidates whose ears are likely tingling. View gallery