Chris Pratt hit the premiere with wife Anna Faris. He plays brash adventurer Peter Quill, who finds himself to be the object of an unrelenting bounty hunt after he steals a mysterious orb coveted by the powerful villain, Ronan.
Bradley Cooper, who plays gun-toting raccoon Rocket, took a selfie with eager fans.
Zoe Saldana, who plays the deadly and enigmatic Gamora, said of the idea that there will be lots of Gamoras running around the streets come Oct. 31: "I can't wait for Halloween!"
Vin Diesel makes his Marvel debut as the tree-like humanoid Groot.
Chris Pratt went with a tailored light gray suit for the blockbuster's screening.
The Mom star accompanied husband Chris Pratt to the premiere of the Marvel film.
James Gunn and Sean Gunn
Director James Gunn's brother, Sean Gunn (right), appears in the movie as Yondu's first mate, Kraglin. "I've been getting bossed around by my brother for a long time, so I was used to it," Gunn said of working with his sibling. He noted that they've been creating movies together since they were little and using a Super 8 camera.
Dave Bautista plays the revenge-driven Drax.
Karen Gillan plays Nebula in the Marvel flick.
'Guardians of the Galaxy'
From left: Benicio Del Toro, director James Gunn, Chris Pratt and Marvel Studios president Kevin Feige.
Aubrey Plaza stepped out to support Pratt, her longtime Parks and Recreation co-star.
Glenn Close, who plays Nova Prime, opted for an all-white ensemble on the red carpet.
Lee Pace plays the film's powerful villain, Ronan.
Agents of SHIELD actress Elizabeth Henstridge hit the red carpet to support Marvel's latest big-screen installment.
Ming Na Wen
Agents of SHIELD actress Ming-Na Wen went with a strapless dress for the premiere.
Marvel Studios president Kevin Feige went with casual kicks for the screening.
Clare Grant and Seth Green
Seth Green stepped out with wife Clare Grant for the Disney/Marvel movie premiere.
Dancing With the Stars' Karina Smirnoff also hit the red carpet wearing white.
Zachary Levi (Chuck) attended the premiere in a patterned suit.