The comedian broke through on the ABC sitcom, starring opposite Pam Dawber as Mork, an alien who comes to Earth from Ork in an egg-shaped spaceship. A spinoff of Happy Days, Mork & Mindy earned Williams his first Emmy nomination for lead actor in a comedy series.
'Good Morning, Vietnam' (1987)
Williams earned a Golden Globe award and a best actor Oscar nomination for his role as Adrian Cronauer, an irreverent DJ, in the war comedy. In 2000, the film landed on AFI's list of the 100 greatest comedies of all time.
'Dead Poets Society' (1989)
Williams earned an Academy Award nomination for his portrayal as John Keating in the critically acclaimed 1989 film Dead Poets Society, with The New York Timescalling it an "exceptionally fine performance."
In this Penny Marshall-directed drama, Williams played a neurologist who uses an experimental drug to try to lift patients out of their catatonic states.
'The Fisher King' (1991)
In 1991's The Fisher King, starring opposite Jeff Bridges, Williams won a Golden Globe for his performance as Parry.
Williams played Peter Pan in Steven Spielberg's adventure film, co-starring Julia Roberts, Dustin Hoffman and Bob Hoskins. The film earned five Academy Award nominations.
Williams voiced the Genie in Disney's classic Oscar-winning animated feature Aladdin, which earned the actor a special award at the Golden Globes in 1993.
'Mrs. Doubtfire' (1993)
In Mrs. Doubtfire, Williams plays an out-of-work voice actor and divorced father, who, in order to be closer to his children, takes on the persona of a Scottish nanny, Euphegenia Doubtfire. Though the movie received mixed reviews, Fox 2000 put a Mrs. Doubtfire sequel in active development back in April with Williams — who won a Golden Globe for his performance — and director Chris Columbus attached.
In Joe Johnson's film, Williams played a man trapped in a board game who's unleashed when two kids (Kirsten Dunst and Bradley Pierce) roll the dice.
'The Birdcage' (1996)
Directed by Mike Nichols,The Birdcage stars Williams as Armand Goldman, a gay cabaret owner. The film grossed $185.3 million worldwide.
'Good Will Hunting' (1997)
Williams won a supporting actor Academy Award for the universally acclaimed Good Will Hunting, penned by then-unknowns Ben Affleck and Matt Damon. It earned $138.4 million in the North American box office and grossed $225.9 million worldwide.
This remake of 1961's The Absent-Minded Professor starred Williams as Professor Philip Brainard, inventor of a green goo-like substance.
'Patch Adams' (1998)
Patch Adams was based on the book Gesundheit: Good Health Is a Laughing Matter, co-written byDr. Hunter "Patch" Adams and Maureen Mylander. Though the film was poorly received, it was still a box-office success, earning $202.3 million worldwide.
'Bicentennial Man' (1999)
Williams starred in this film, based on a novel by Isaac Asimov and Robert Silverberg, about an android who develops the capacity to experience human emotions.
'Death to Smoochy' (2002)
Williams played one of two clowns alongside Edward Norton in this dark comedy directed by Danny DeVito.
Williams starred as crime writer Walter Finch in this Christopher Nolan-directed psychological thriller. Al Pacino and Hilary Swank also starred.
'One Hour Photo' (2002)
Williams took a dark turn starring in the well-received psychological thriller One Hour Photo as aSavMart photo technician who secretly makes copies of customers' negatives.
Williams lent his voice to 20th Century Fox's Robots as Fender, a robot scraping by through taking souvenir photos and selling maps to the stars' homes.
'Night at the Museum' (2006)
In the comedy-adventure feature Night at the Museum, Williams plays President Teddy Roosevelt, who explains why the museum comes to life in the evenings. The success of the 2006 movie prompted a 2009 sequel, Battle of the Smithsonian, and launched a third film, Secret of the Tomb, scheduled to be released Dec. 19.
'Happy Feet' (2006)
Williams voiced Ramon and Lovelace in the animated flick about a group of lovable penguins. Happy Feet won the Academy Award for best animated feature. Williams reprised his roles in the 2011 sequel, Happy Feet 2.
'Old Dogs' (2009)
Williams teamed up with John Travolta for the comedy about two men forced to raise children together. The film was panned by critics — receiving just a 5 percent on Rotten Tomatoes — but went on to earn $96.5 million worldwide on its $35 million budget.
'The Crazy Ones' (2013-14)
Williams returned to the small screen after more than three decades with a starring role in CBS' David E. Kelley-created comedy The Crazy Ones, where he played the head of a Chicago ad agency and the father of Sarah Michelle Gellar's character. "It's gotten to this place of comfortable — in a good way," Williams told The Hollywood Reporter in February.