Jennifer Aniston is about to get "Derailed." The actress will star opposite Clive Owen in the Miramax Films feature based on James Siegel's best-selling novel. Lorenzo di Bonaventura produces. The film will mark Academy Award winning director Mikael Hafstrom's English-language directorial debut. Based on a script by "Collateral" scribe Stuart Beattie, "Derailed" revolves around a married advertising executive whose life takes an unpredictable turn when he misses his train to work. Production is scheduled to begin in the fall in London and Chicago. Executive vp production Jon Gordon and senior vp creative affairs Jennifer Wachtell will oversee the production on behalf of Miramax. The deal was negotiated for Miramax by executive vp business affairs Steve Hutensky and senior vp business and legal affairs Barry Littman. CAA negotiated on behalf of Aniston.