Simon Baker will star in "Sex and Death 101," Dan Waters' dark comedy being produced by Cary Brokaw's Avenue Pictures and Sandbar Pictures. The story follows a man (Baker) whose life is upended by a mysterious e-mail containing the names of every woman he has had sex with and, eerily, every woman he will have sex with in the future. Waters, who wrote "Heathers" and "Batman Returns," penned the script and is directing. Avenue and Sandbar are financing. Brokaw is producing with Sandbar's Lizzie Friedman and Greg Little. Avenue exec vp Aaron Craig Geller, who brought in the project, is serving as executive producer. A mid-May shoot in Vancouver is being targeted. Baker, repped by ICM and Untitled, last starred in the romantic comedy "Something New," George A. Romero's "Land of the Dead" and in CBS' "The Guardian." He next appears in "The Devil Wears Prada."