THR's Women in Entertainment 2011: Power 100

"Artists need to be much more entrepreneurial and self-starters as far as what they're doing, creating opportunities for themselves, creating businesses," Bohan says about how the industry has changed for talent.

Her superstar comedy clients (and sometime collaborators) Tina Fey and Steve Carell are certainly great role models for that prescription, frequently moving between TV and film and often co-writing and producing their own material. (Fey's book, Bossypants, hit No. 1 on The New York Times best-seller list this year.)

PHOTOS: THR's 2011 Women in Entertainment Power 100

As a married mother of three (ages 9, 7 and 5), Bohan can relate to the difficult working-mother dynamic that Fey and new client Maya Rudolph perpetually juggle. "I so admire women who don't stop pursuing their dreams because they're confined to one role, which is being a mother," she says.

Bohan also picked up longtime Saturday Night Live writer Paula Pell, an "undiscovered gem" whom she's helped move into features with writing on Date Night; Judd Apatow's This Is Forty; an untitled comedy at Universal that Fey is producing; Bridesmaids; and Wanderlust. "What I love about Paula's story is that it's never too late," says Bohan, who notes that Carell and Fey also found stardom close to 40. "It flies in the face of the idea that it's only the young people who can really emerge, and it just gives me such pride and possibility."

Clients Julianna Margulies (The Good Wife), Amy Adams (The Fighter, The Muppets, Man of Steel) and Lucy Punch (Powers, Bad Teacher) have had strong years, and Bohan signed Thor baddie Tom Hiddleston, who also has a role in Steven Spielberg's War Horse.

A self-proclaimed "Cali girl" from Westlake Village who now lives in Santa Monica, Bohan spent 10 days in August sailing the South Pacific with her boating husband and their kids, sleeping and eating onboard and swimming with sharks. "It was one of the most extraordinary trips ever," she says. "My husband is trying to talk me into taking a year off and sailing around the world."