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Billy Crystal, Helen Mirren Spoof 'When Harry Met Sally' (Video)

The duo's Funny or Die clip is a "sequel" to Crystal's 1989 movie with Meg Ryan that also features Mike Tyson -- and a shocking twist.

Billy Crystal spoofs his beloved 1989 hit film When Harry Met Sally in a clip for Funny or Die.

The premise is that Sally (Meg Ryan) has died and Crystal's aged Harry finds a second soulmate in Sharon, played by Helen Mirren.

Crystal and Rob Reiner -- who directed the original movie -- pitch the idea of a sequel to some movie executives, including one played by Parks and Recreation's Adam Scott, who suggests a shocking, hilarious twist that you have to see for yourself.

Mike Tyson, comedian Rob Riggle, Maya Rudolph and Glee's Mike O'Malley also pop up in the video.

Watch the clip below.