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'Grey's Anatomy' First Look: Watch Neve Campbell's Lizzie Reunite With Derek (Video)

In a clip from Thursday's episode, Heather is put in the middle of a very awkward Shepard family reunion.

Grey's Anatomy Neve Campbell - H 2012
ABC/RON TOM
"Grey's Anatomy's" Neve Campbell and Tina Majorino

It's a Shepherd family reunion on Thursday's intern-centric episode of Grey's Anatomy.

During Thursday's "Love Turns You Upside Down" episode of the ABC medical drama, Neve Campbell makes her debut as Derek's previously unnamed fourth sister, Lizzie, when Meredith asks intern Heather (Tina Majorino) to reach out to his sisters in an attempt to get a nerve donated to help repair his hand.

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While Derek (Patrick Dempsey) asks Heather to call the Shepard sisters off, Meredith (Ellen Pompeo) has other orders and the poor intern finally snaps when she's caught in the middle, ultimately telling the married couple that his siblings are out for blood. But just in the middle of her tirade, in walks Dempsey's former Scream 3 co-star.

Check out the clip below and hit the comments with why you think Lizzie is less than thrilled to see Derek and Meredith. Do you think she'll be able to help repair Derek's hand? Grey's Anatomy airs Thursdays at 9 p.m. on ABC.

Email: Lesley.Goldberg@thr.com; Twitter: @Snoodit