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Rosie O'Donnell to Take Over Oprah's Chicago Studio for OWN Show

"There is an enormous personal respect and value to that little bit of real estate to Oprah,” says Sheri Salata, president of Harpo Studios.

Rosie O'Donnell is taking over Oprah Winfrey's former soundstage in Chicago, she announced Tuesday morning in a video to Harpo staffers.