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Rose Byrne ("Damages")
Currently on the big screen as a model-turned-pop star, opposite Russell Brand and Jonah Hill, in the comedy "Get Him to the Greek." Is filming James Wan's "Insidious," opposite Patrick Wilson, playing the mother of a child haunted by a paranormal being. Also cast in Judd Apatow's upcoming untitled Kristin Wiig project.
Glenn Close ("Damages")
In October she'll film the lead role in "Albert Nobbs," a project she also co-produces and co-wrote, about a woman who must pass as a man to work in 19th century Ireland. The movie co-stars Amanda Seyfried and Orlando Bloom.
Elisha Cuthbert ("24")
Has the lead role in ABC's fall comedy "Happy Endings," playing a bride who splits with her groom at the altar.
Emilie de Ravin ("Lost")
Lends her voice to the animated "Legend of the Guardians: The Owls of Ga'Hoole," out in the fall.
America Ferrera ("Ugly Betty")
Will next be seen as the wife of an Iraq War veteran who returns home in "The Dry Land," which she also executive produced, opposite Jason Ritter and Melissa Leo. Recently inked a deal with MTV to produce a telenovela version of "Romeo and Juliet," called "Pedro and Maria."
Ali Larter ("Heroes")
Reprises the role of Claire Redfield in the sequel "Resident Evil: Afterlife," out in the fall.
Hayden Panettiere ("Heroes")
Voices the role of Kate, a young wolf, in Lionsgate's animated "Alpha and Omega," about a pair of wolves captured by park rangers, out in September.
Mary Lynn Rajskub ("24")
Just opened her one-woman stage show, "Mary Lynn Spreads Her Legs," at the Steve Allen Theatre, based on her own experiences adjusting to motherhood.
Joely Richardson ("Nip/Tuck")
Portrays young Queen Elizabeth I in Roland Emmerich's upcoming Shakespeare conspiracy thriller "Anonymous," with Rhys Ifans and Richardson's mother, Vanessa Redgrave.
Sonya Walger ("Lost, FlashForward")
Cast in the psychological thriller "The Factory," opposite John Cusack and Jennifer Carpenter, about an obsessive cop whose hunt for a serial killer turns personal when his daughter goes missing. From producer Joel Silver.
Vanessa Williams ("Ugly Betty")
On Broadway starring in the new musical revue "Sondheim on Sondheim," which also stars Barbara Cook and Tom Wopat.