The multihyphenate is building a Hollywood empire with female-fronted hits ('Broad City,' 'Russian Doll') and her feature directorial debut ('Wine Country') starring 'SNL' pals including Tina Fey and Maya Rudolph, all  while dealing with the relentless outrages of the political moment: "It's really hard to not have a full-on panic attack every day."

Marvel Studios and Disney's three-hour epic sendoff reunites the franchise's mightiest superheroes to battle Josh Brolin's Thanos.