Tom Hanks, Rita Wilson

Tom Hanks poses with wife Rita Wilson at the movie's premiere.

Halle Berry, Tom Hanks, Susan Sarandon

Tom Hanks is flanked by co-stars Halle Berry (in Dolce & Gabbana) and Susan Sarandon. Hanks, Berry and Sarandon play multiple characters in the movie.

Zhu Zhu

The Chinese actress co-stars in the movie, which hits theaters Oct. 26.

Tom Hanks, Rita Wilson

In the movie, Hanks plays multiple characters, including an old man telling stories around a campfire and a crooked doctor on a Pacific sea voyage in 1849.

Georgia King

The actress co-stars on the freshman comedy series The New Normal.

Keanu Reeves

Keanu Reeves starred in The Matrix trilogy for the Wachowski siblings, who directed Cloud Atlas with Tom Tykwer.

Keith David

Andy Wachowski, Lana Wachowski, Tom Tykwer

Writer-directors Andy Wachowski, Lana Wachowski and Tom Tykwer pose at the film's premiere. Lana Wachowski recently gave a much-lauded speech at the Human Rights Campaign’s gala fundraising dinner in San Francisco, in which she spoke about growing up transgender.

EXCLUSIVE VIDEO: Lana Wachowski Reveals Suicide Plan, Painful Past in Emotional Speech

Jim Sturgess

Jim Sturgess arrives at the Cloud Atlas premiere. Among the characters he plays in the film are an 18th century sailor and a freedom fighter in 2144 “Neo Seoul."

Xun Zhou

Chinese actress Xun Zhou is one of several actors who plays a character of a different race than their own in Cloud Atlas.

Doona Bae

Korean actress Doona Bae attends the premiere of Cloud Atlas, which is her English-language debut. One of her characters in the film is Sonmi-451, a genetically engineered fabricant.

Halle Berry

Halle Berry wears metallic lace at the Los Angeles premiere of Cloud Atlas at Grauman's Chinese Theatre.