Box Office Preview: Can 'Detective Pikachu' Dethrone 'Avengers: Endgame'?

Detective Pikachu-Publicity Still-H 2018
Courtesy of Warner Bros. Pictures
'Endgame' is looking to pick up $75 million at the domestic box office in its third weekend.

Avengers: Endgame has sat at No. 1 at the box office for the past two weeks, with little competition. 

The pic is looking to pick up around $75 million at the domestic box office in its third weekend, according to those with access to early surveys, adding to its massive $2.303 billion at the global box office. But the Marvel Studios title could end up vying for that No. 1 spot with newcomer Pokémon Detective Pikachu

The Legendary and Warner Bros. action adventure is tracking for an impressive $55 million to $60 million bow, according to those with access to early tracking numbers. While those numbers are coming in below Endgame projections, some experts are expecting a larger debut for Pikachu that could have it usurp Endgame stateside.

Ryan Reynolds voice stars as the titular Pikachu in the movie that sees the popular Pokemon team up with a human counterpart Tim (Justice Smith), who has the ability to understand what Pikachu is saying. Together they set off to solve the mystery of Tim's missing father.

Detective Pikachu has been earning mainly positive reviews (it currently sits at 67 percent) and is opening wide in 4,200 North American theaters.

Also debuting over Mother's Day weekend are two female-fronted offerings, MGM's The Hustle and STX and eOne's Poms.

A gender-bent remake of Dirty Rotten Scoundrels, The Hustle stars Anne Hathaway and Rebel Wilson as scam artists — one high-end and one low-rent — that team to fleece unsuspecting victims. Box office observers are estimating earnings around $12 million for the pic, which is opening on 3,007 screens in North America. 

Diane Keaton and Jackie Weaver lead Poms, an ensemble dramedy about a group of women who start a cheerleading team in a retirement community. Early surveys have the film, which is set to launch in 2,750 theaters, taking in somewhere between $7 million to $10 million.