VIDEO: Behind the Scenes of THR's Rule Breakers 2011 Magazine Shoot

Issue 47 Cover Split - P 2011
Bridgette Sire/Robyn Twomey/Kwaku Alston

Issue 47 Cover Split - P 2011

Nine months in the making, The Hollywood Reporter's inaugural year-end portfolio of entertainment's biggest risk takers features a who's-who of Hollywood.

STORY: Chuck Lorre's Sheen-Kutcher Gamble, Netflix Gone Awry, Kardashian Brand's 72-Day Wild Ride: THR Features 2011's Biggest Rule Breakers

The 22-page special issue, out this week, includes industry veterans -- George Lucas, James Cameron, Diane Sawyer, Matt Lauer, among others -- TV newcomers Liz Meriweather and Zooey Deschanel of Fox's New Girl as well as Suburgatory's Emily Kapnek and Jane Levy -- and familiar faces, like Kim Kardashian, Kris Jenner and Betheny Frankel.

"I think it's great when a movie like this does well because I hear that women are more than half the population; so shouldn't half of the movies, or 52 percent be like this?" Bridesmaids rule-breaker Judd Apatow jokes during the shoot. Adds star Melissa McCarthy, "I don't know, I can't do numbers!"

PHOTOS: 2011's Biggest Rule Breakers Kim Kardashian, Netflix's Reed Hastings, Chuck Lorre and Ashton Kutcher: THR Year In Review

Go on the creepy set of FX's American Horror Story and visit the Warner Bros. Television lot for Two and a Half Men as THR offers a look behind the scenes of the inaugural Rule Breakers issue.