Diablo Cody, Oprah Winfrey Team for HBO Comedy (Exclusive)

The untitled comedy is based on Dr. Julie Holland's upcoming book "Moody Bitches."
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Diablo Cody and Oprah Winfrey

HBO is teaming with Diablo Cody and Oprah Winfrey to explore "moody bitches."

The premium cable network is developing an untitled comedy based on Dr. Julie Holland's upcoming book, Moody Bitches, The Hollywood Reporter has learned exclusively.

Holland's book -- Moody Bitches: The Truth About the Drugs You're Taking, the Sex You're Not Having, The Sleep You're Missing and What's Really Making You Crazy -- explores the pros and cons of the drugs people are being offered as well as some surprising and highly effective natural therapies. HBO's take, which is inspired by Holland's source material, will "expose the truth about the drugs you're taking, the sex you're not having, the sleep you're missing and what's really making you crazy."

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Cody -- who will be credited as a creator on the potential series -- will pen the script and executive produce alongside Winfrey and her Harpo Films banner. Harpo first inked a long-term pact with HBO in late 2008 to develop movies, miniseries, documentaries and scripted series for the premium cabler. Holland will be credited as a co-exec producer.

The untitled Cody comedy marks Harpo's latest scripted project at HBO. It joins These Things Happen, a modern family comedy based on Richard Kramer's (My So-Called Life) novel of the same name, and last year's untitled drama about the first black president at a prestigious liberal arts college.

For Cody, the project becomes the Juno Oscar-winning screenwriter's latest small-screen sale. Cody also has Prodigy, a teen drama set up at Fox with Fake Empire's Josh Schwartz and Stephanie Savage. In addition, the United States of Tara alum also has her TBS talk show pilot, Me Time With Diablo Cody, in the works and last year developed comedy Alex + Amy for ABC.

Moody Bitches becomes the latest work from psychiatrist/author Holland to get the small-screen treatment. Her 2010 book Weekends at Bellevue: Nine Years on the Night Shift at the Psych ER was adapted at Fox and went to pilot in 2011. The Janet McTeer and Lauren Ambrose drama did not move forward. A publication date for Moody Bitches has not yet been announced. 

Cody is with WME, MXN Entertainment and McKuin Frankel. Winfrey is repped by WME.

E-mail: Lesley.Goldberg@THR.com
Twitter: @Snoodit