'Grey's Anatomy's' Ellen Pompeo on What's Next for Meredith

Grey's Anatomy 1 Still - H 2015
Courtesy of ABC

Grey's Anatomy 1 Still - H 2015

[Warning: This story contains spoilers from the April 23 episode of Grey's Anatomy.]

Following Thursday's shocking Grey's Anatomy in which leading man Patrick Dempsey's Derek Shepherd was killed off, star Ellen Pompeo on Monday weighed in on what's next for Meredith.

Read more 'Grey's Anatomy' Shocker: Star Patrick Dempsey Exits

Derek "McDreamy" Shepherd, half of the show's central couple, was dramatically killed off the series, delivering a massive blow to Grey's Anatomy.

See more 'Grey's Anatomy's' Famous Departures

"I have always said what keeps me going is the fans," Pompeo wrote in an extended Twitter posting. "Knowing we move you and inspire you. There are so many people out there who have suffered tremendous loss and tragedy. Husbands and wives of soldiers, victims of senseless violence and parents who have lost children. People who get up each day and do what feels like is the impossible. So it is for these people and in the spirit of resilience I am honored and excited to tell the story of how Meredith goes on in the face of what feels like the impossible. I hope you will all join me on her journey."

more 'Grey's Anatomy's' Shonda Rhimes Explains Patrick Dempsey's Departure

While leads exiting their series are a routine part of television — Josh Charles was famously killed off on CBS' The Good Wife last season and the show's Archie Panjabi will depart this year — Derek's death was different, as Dempsey still had a year remaining on his contract that would have kept him in the Grey's fold through season 12. Here, Dempsey's Grey's Anatomy co-stars as well as cast members from Scandal and Murder pay their respects and mourn the loss of McDreamy. 

Read more 'Grey's Anatomy' Star on Patrick Dempsey's Departure: It's a "Fundamental Change"

According to a Hollywood Reporter poll, 67 percent of Grey's Anatomy fans voted that they are "McDone" with the Shonda Rhimes drama after Derek's death.

Grey's Anatomy returns Thursday with a two-hour episode starting at 8 p.m. on ABC. Will you be watching? In the meantime, here's ABC's farewell to McDreamy: