Kirstie Alley Joins 'Scream Queens' as Season 2 Series Regular

Kirstie Alley - Headshot - P - 2016
Brian Doben

Kirstie Alley is making her return to broadcast television.

The Emmy- and Golden Globe-winning Cheers alum has joined season two of Scream Queens as a series regular, The Hollywood Reporter has learned.

The second season will see Fox's comedy-horror anthology series move from a college campus to a hospital called the C.U.R.E. Institute, where some of the most fascinating and bizarre medical cases are under observation. Alley will play a brilliant and devious administrator at the hospital.

The actress joins fellow new regulars John Stamos, Taylor Lautner and James Earl. Season one stars Jamie Lee Curtis, Emma Roberts, Lea Michele, Abigail Breslin, Keke Palmer, Billie Lourd, Glen Powell and Niecy Nash all are poised to reprise their roles from season one.

Alley's addition — her first series-regular role since her short-lived 2013 TV Land sitcom Kirstie — is the latest casting coup for Ryan Murphy and his Scream Queens co-creators Brad Falchuk and Ian Brennan. In addition to impressive Glee guest stars like Gwyneth Paltrow and Kate Hudson, Murphy has recently made headlines for luring A-list talent like John Travolta, Alley's former Look Who's Talking co-star, and Lady Gaga to the small screen for roles in The People v. O.J. Simpson and American Horror Story, respectively. For Murphy's upcoming FX anthology drama Feud, he's already lined up the likes of Susan Sarandon and Catherine Zeta-Jones, in addition to American Horror Story vet Jessica Lange.

Alley is best known for her Emmy-winning role on Cheers. She went on to star in the NBC sitcom Veronica's Closet, Showtime's short-lived Fat Actress and Kirstie. The actress most recently guest-starred on Will Arnett's Netflix comedy Flaked. She also competed on seasons 12 and 15 of Dancing With the Stars. Alley is repped by APA, Untitled and Meyer Felsen.

Scream Queens is set to return for season two on Tuesday, Sept. 20, at 9 p.m. ET/PT on Fox.