Jessica Biel and Zooey Deschanel Duke It Out in 'New Girl' Premiere

New Girl Ep401 Last Wedding Still Jessica Biel Zooey Deschanel - H 2014
Ray Mickshaw/FOX

New Girl Ep401 Last Wedding Still Jessica Biel Zooey Deschanel - H 2014

Let's not be coy. The New Girl season premiere finds each member of the game trying to accomplish the same goal: getting laid during the final wedding of a nuptials-filled summer.

But Jess (Zooey Deschanel) has an obstacle in her quest to shack up with a charming wedding guest played by Veep's Reid Scott in the form of fellow guest star Jessica Biel.

"There's always that other girl there, when you're in that situation, that just seems like a better version of you," says episode scribe J. J. Philbin. "It's so fun to be able to work on a show where the women make you laugh so hard."

Of the evenly-paired duo, Biel's character does present a tough act to compete with. She's a doctor. "Have you ever heard of plutoxic syndrome?" she says to a shrug. "It's because I cured it. You're welcome, vaginas everywhere."

You're welcome, indeed. Watch the preview below before "The Last Wedding" bows Tuesday night at 9 p.m. on Fox.