'Up All Night' Creator Emily Spivey Exits Series

Christina Applegate Will Arnett Up All Night 2012

Up All Night creator Emily Spivey has become the latest casualty of the NBC comedy.

Ahead of its reboot from a single- to multicamera series, the creator of the sophomore vehicle has opted to part ways with the second-year comedy, The Hollywood Reporter has confirmed.

STORY: NBC's 'Up All Night' Changes Showrunners as Multicamera Switch Nears

Spivey's exit comes a month after showrunner Tucker Crawley was replaced by Nurse Jackie's Linda Wallem as NBC and studio Universal Television opted to make some creative changes to the struggling Christina Applegate-Will Arnett-Maya Rudolph series at its midseason point.

Crawley, for his part, replaced original showrunner Jon Pollack. The former departed in December to work as a consulting producer on Fox's The Mindy Project, which is produced by Universal Media Studios.

STORY: 'Up All Night' Adds Episodes, Switches to Multicamera Format

The modestly rated Up All Night will resume production in February, after a three-month hiatus, with three additional episodes tacked on to its initial order of 16. At that time, the Lorne Michaels-produced comedy will transition from singlecamera to a generally cheaper and often broader multicamera format, a process that has entailed building new soundstages to be able to film the series in front of a live studio audience.

Up All Night will return to NBC in April or May. The creative change marks the second for the comedy this year after the Rudolph's talk-show format was ditched in the season two premiere earlier this fall. All of the tweaks come as NBC looks to refresh their comedy brand as a destination for more broadly appealing fare, which entertainment chief Jennifer Salke outlined in an interview with The Hollywood Reporter last month.

Email: Lesley.Goldberg@thr.com; Twitter: @Snoodit