6:45pm PT by Ashley Lee
Jared Leto Talks AIDS at MTV Movie Awards: 'The Epidemic Rages On' (Video)
Leto won the award for best onscreen transformation, over American Hustle's Christian Bale, The Hunger Games: Catching Fire's Elizabeth Banks, Orlando Bloom in The Hobbit: The Desolation of Smaug, and his Dallas Buyers Club co-star Matthew McConaughey.
Lupita Nyong'o presented the award, with Leto thanking her: "It's an award in itself to get that from her."
Wearing a sparkling black blazer, he began his acceptance speech by thanking the film's fans as well as his 30 Seconds to Mars bandmates. To the category's voters, he said, "You honor not only me, but the hard work and dreams of so many."
Leto then took a serious turn from the lighthearted awards show. "We've made a lot of progress in the battle against AIDS, but it's not time to celebrate just yet. There's no cure; the epidemic rages on. But here's to the hope that one day we'll put an end of this plague, and the world will rejoice knowing that no one will ever have to suffer the indignation of this sickness again, nor the intolerance, the fear or the prejudice that lives alongside it."
He continued, "Love who you want to love, live how you wish to live and never let anyone ever stop you from turning your dreams into your reality."