Kid actor Izabela Vidovic is also boarding the production, which is expected to get underway Sept. 24 in New Orleans with Gary Fleder directing.
The project, based on a book by Chuck Logan, centers on a an ex-DEA agent (Statham) who moves to a small town in the hope of a quiet life but runs afoul of a villainous meth kingpin named Gator (Franco).
Ryder will play a former biker chick partnered with Franco. Vidovic is playing Statham’s daughter.
Stallone is producing with Kevin King Templeton and Rene Besson. Avi Lerner and Trevor Short executive produce.
Ryder just wrapped The Iceman, a thriller starring Chris Evans and Michael Shannon, for Millennium. She also voiced a character in Tim Burton’s Frankenweenie.
Ryder is repped by Gersh and Hirsch Wallerstein.