'Alex Cross' Trailer Pits Tyler Perry Against Matthew Fox (Video)

The actor-director co-stars with the "Lost" alum in the latest installment of James Patterson's franchise.

If you're a fan of the former Fox castaway drama Lost, and Matthew Fox as the show's hero-protagonist Dr. Jack Shepard, then you might be slightly taken aback by his portrayal of a serial killer in the upcoming Alex Cross thriller.

The trailer for Alex Cross, featuring Tyler Perry taking over Morgan Freeman's role as titular detective, shows Fox as a bald homocidal maniac named "Picasso" and described by Cross as "ex-military, special forces, judging by his tactics." Among Picasso's creepiest lines:  "I'm fascinated ...  by pain."

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But Cross, heroically vowing to protect his wife, is no shrinking violet.

"I'm gonna meet him at the gates of hell before I let him take a person that I love from me," he declares.

Directed by Rob Cohen, Alex Cross opens October 19 and also stars Ed Burns and Cicely Tyson in the continuing saga of James Patterson's book-to-film franchise.