Box Office Preview: 'Avengers: Age of Ultron' Set to Crush 'Hot Pursuit'

'Hot Pursuit' marks one of the worst reviewed films of Reese Witherspoon's career; 'Age of Ultron' will jump the $700 million mark globally sometime on Wednesday.

Joss Whedon's Avengers: Age of Ultron will continued to dominate the box office over Mother's Day weekend, while Reese Witherspoon and Sofia Vergara comedy Hot Pursuit is hoping to generate enough interest among women to open in the high teens.

Anne Fletcher directed the two actresses in the MGM and New Line comedy, which goes out through Warner Bros. MGM and Witherspoon's company, Pacific Standard, ran production on Hot Pursuit, starring Witherspoon as an inept police offer who must protect the widow of a drug dealer from criminals and corrupt cops.

So far, the $35 million movie is one of the worst reviewed films of Witherspoon's career. The actress was last in theaters in Wild, the Fox Searchlight title that earned her an Oscar nomination.

The weekend's other new nationwide offering is Jack Black comedy The D Train, which IFC Films opens in more than 800 theaters, marking its widest release ever. The film, directed by Jarrad Paul and premiering at the Sundance Film Festival earlier this year, is tipped to gross $2 milllion-$3 million.

Age of Ultron is expected to drop 50 percent-60 percent in its second outing. If it falls 55 percent, that means $85 million for the weekend. The Disney and Marvel Studios tentpole jumped the $200 million mark in only four days, the fastest of all time after The Avengers (three days).

Through Tuesday, the movie's domestic total is $217.6 million. Overseas, where it opened a week ahead of its domestic launch, it has earned a mammoth $478.2 million for a worldwide total of $695.9 million.

Making a limited play is Maggie, the Arnold Schwarzenegger-Abigail Breslin zombie thriller that Roadside Attractions opens in 76 theaters.

And Sony Pictures Classics opens Saint Laurent in four theaters in New York and Los Angeles.