Hollywood Reacts to Jerry Lewis' Death

"Even at 91, he didn't miss a beat… Or a punchline. You'll be missed," said Robert De Niro in a statement.

Legendary comedian Jerry Lewis died Sunday morning at his home in Las Vegas, publicist Candi Cazau confirmed. He was 91.

Lewis dominated show business with Dean Martin in the 1950s and became Paramount's biggest star in the 1960s which gave him creative freedom with the studio. He had memorable roles in classics including The Bellboy (1960) and The Nutty Professor (1963).

Lewis was also devoted to fighting against muscular dystrophy. He hosted an annual Labor Day telethon which raised almost $2.5 billion and was nominated for a Nobel Peace Prize in 1977 for his efforts.

Lewis' health issues consisted of open-heart surgery in 1983, surgery for prostate cancer in 1992, treatment for his dependence on prescription drugs in 2003, a heart attack in 2006 and a long bout with pulmonary fibrosis, a chronic lung disease.

"Jerry was a pioneer in comedy and film. And he was a friend," said Robert De Niro in a statement. "I was fortunate to have seen him a few times over the past couple of years. Even at 91, he didn't miss a beat… Or a punchline. You'll be missed."

The White House press secretary's office also issued a statement:

"Jerry Lewis kept us all laughing for over half a century, and his incredible charity work touched the lives of millions. Jerry lived the American Dream — he truly loved his country, and his country loved him back. Our thoughts are with his family today as we remember the extraordinary life of one of our greatest entertainers and humanitarians. Thank you, Jerry. You will be missed."

As news of his death spread on Sunday, other tributes flooded in from Hollywood via social media. See the posts below.