Donald Sutherland Struggles With Alzheimer's in 'The Leisure Seeker' (Exclusive Video)

Helen Mirren co-stars in the road trip dramedy, directed by Paolo Virzi.

Helen Mirren is upbeat alongside Donald Sutherland in The Hollywood Reporter's exclusive clip of The Leisure Seeker.

Mirren stars in the dramedy as Ella, who is dying of cancer, opposite Sutherland as John, a retired professor who is suffering from Alzheimer's disease. Rather than spending their last days in a nursing home or a hospital bed, they dust off their titular vintage RV for a final road trip from Boston to Key West.

The Sony Pictures Classics release is based on Michael Zadoorian's 2009 novel, and marks the English-language debut of Italian director Paolo Virzi (Like Crazy). It made its world premiere at the Venice Film Festival and screens next at the Toronto Film Festival.

The Leisure Seeker hits theaters Jan. 19.