Oprah Winfrey: "I Was Genuinely Nervous to Take on the Role" in 'Henrietta Lacks' | Drama Actress Roundtable

"I come as a person who has great respect for the craft of acting, but not really developing the craft," said the media mogul and Oscar nominated actress and producer.

"I was afraid of making a fool of myself," Oprah Winfrey told The Hollywood Reporter during the Drama Actress Roundtable on taking on The Immortal Life of Henrietta Lacks. Winfrey was nominated for an Oscar for her supporting role in The Color Purple"It's a very intimidating thing. I don't take it lightly."

"I have such regard for what it takes to dismantle yourself, open yourself up vulnerably, and let the energy and spirit of another character come through that," said Winfrey on the craft of acting.

"I keep trying to share with the world what it means not just to be sexually violated, but what it means to have someone who's a predator in your own space, in your own environment and to be prayed upon," Winfrey told THR of what draws her to tell certain stories. "[I'm] all about sharing the story that is going to raise consciousness on any level."

More roundtables featuring comedy and drama actresses, actors, showrunners and reality creators will continue through July in print and online. Tune in to new episodes of Close Up With The Hollywood Reporter starting May 25 on Sundance TV, and look for clips at THR.com/topic/roundtables with full episodes on THR.com after broadcast.