'Tammy': Melissa McCarthy, Susan Sarandon on Comedic Falls and That 'Thelma & Louise' Selfie

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Melissa McCarthy and Ben Falcone

"He’s my favorite person to work with — and to marry," said McCarthy of director-husband Ben Falcone at the L.A. premiere.

Comedy took over Hollywood on Monday night at the TCL Chinese Theatre for the Los Angeles premiere of Ben Falcone's directorial debut, Tammy, starring his wife, producer and co-writer Melissa McCarthy.

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"I learned that he’s a great director — it was fun every single day, it was calm and happy and a really, really lovely set and I love the movie he put together," McCarthy said on the red carpet of Falcone. "He’s my favorite person to work with — and to marry."

Co-star Susan Sarandon echoed McCarthy's sentiments. "I thought that it was an untraditionally collaborative atmosphere and that he made everyone feel very safe," Sarandon told The Hollywood Reporter at the film's afterparty, adding of the onscreen couple, "They were really fun because you could throw something out and they would just go along with it. I mean, I can't tell you how many different versions of every single scene there are! I really had a great time."

Sarandon also commented on reuniting with her Thelma & Louise co-star Geena Davis for her THR cover shoot. "We realized that, in fact, our little Polaroid in Thelma & Louise was a very early-on selfie!" she laughed, also pointing out the shot from the THR re-creation that went viral. "My dog [also] tweeted it, and then everybody picked it up."

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Tammy follows a woman who hopes to recover from a horrible day — totaled car, lost job, cheating husband — with a road trip with her adventurous grandmother. Castmates Mark Duplass, Sarah Baker, Mia Rose Frampton, Rich Williams and producer Will Ferrell also hit the premiere for Falcone's directorial debut.

"I think that everybody knows somebody like Tammy, and maybe everybody has been somebody like Tammy for a little bit of their lives — I know I have," Falcone said before the screening. "There are people that you know that maybe have potential and they could do these great things, but something holds them back. ... There’s something about Tammy that speaks to a large amount of people."

Cast and crew celebrated the movie’s premiere with an afterparty at Mel's Drive-In on Highland Avenue, which transformed into the film’s Topper Jack’s joint. An assortment of upscale diner food was served, including vegan chili, grilled cheese sandwiches, miniature sliders, root beer floats and ice cream shakes.

Tammy, which also features Nat Faxon, Toni ColletteAllison Janney, Gary Cole, Dan Aykroyd, Sandra Oh and Kathy Bates, opens July 2.