Toronto: Melissa McCarthy's 'St. Vincent,' James Franco's 'The Sound and the Fury' Complete Star-Studded Lineup

Melissa McCarthy

She positively blew up after co-starring in the Apatow-produced Bridesmaids; also appears in This is 40.

Denzel Washington, Reese Witherspoon and Robert Duvall to appear in conversation at the Canadian film festival

Melissa McCarthy's comedy St. Vincent and the Roger Waters concert documentary The Wall are to get world premieres at the upcoming Toronto Film Festival.

Bill Murray plays the eponymous Vincent opposite McCarthy in Theodore Melfi's comedy, with Naomi Watts, Terrence Howard and Chris O'Dowd co-starring in The Weinstein Co.'s release.

Fest organizers, completing their full film lineup with Tuesday's announcements, will debut The Wall, filmed during Waters' 2010-2013 The Wall Live tour.

The Special Presentations sidebar also booked a North American premiere after Venice for James Franco's adaptation of the William Faulkner novel The Sound and the Fury, co-starring Tim Blake Nelson and Seth Rogen.

High-profile documentary bookings in the Maverick section include a world bow for David Thorpe's Do I Sound Gay?, including interviews with George Takei, David Sedaris and fashion guru Tim Gunn, and a Canadian premiere for The 50 Year Argument, directed by Martin Scorsese and David Tedeschi.

The Maverick sidebar includes an international bow for Julie Taymor's A Midsummer Night's Dream, and in-person conversations with Denzel Washington and Antoine Fuqua, who reunite in Toronto with The Equalizer, Oscar winner Juliette Binoche, Reese Witherspoon, Richard Gere, Robert Duvall and Jon Stewart.

The Discovery program has world bows for Adult Beginners, where producer Ross Katz (Lost in Translation, Marie Antoinette) directs and Nick Kroll, Rose Byrne and Bobby Cannavale co-star, Debbie Tucker Green's Second Coming, starring Idris Elba and Nadine Marshall, and Morgan Matthews' Sally Hawkins starrer X+Y.

Toronto, which sorted through 5,167 submissions, will screen 285 features during its September 4-14 run.

That includes 143 world premieres, 34 international bows and 73 North American premieres.

Stars to hit the red carpet outside Roy Thomson Hall and other festival venues include Channing Tatum, Keira Knightley, Benedict Cumberbatch, Tobey Maguire, Kate Winslet and John Travolta.

Also to show gala film launch style in Toronto are Ben Stiller, Ryan Reynolds, Salma Hayek, Tina Fey, Jennifer Aniston, Steve Carell, Kevin Costner, Anna Kendrick, Michael Douglas and Robert Downey Jr.

Fest organizers also promise red carpet appearances by Mark Ruffalo, Simon Pegg, Julianne Moore, Amanda Seyfried, Diane Keaton, Jane Fonda, Jennifer Connelly, Robert Duvall and Morgan Freeman.

Toronto has no official competition, but will hand out top audience awards on September 14 just as the awards season kicks into gear.